L-Theanine is often overshadowed by its
more famous cousins, but it packs a powerful punch. An amino acid
found in green tea, L-Theanine
is well-documented for its calming, yet non-sedative, effects.
The L-Theanine used in Proloftin is a patent-protected version
called Suntheanine®. Suntheanine is the only 100 percent L-Theanineproduct
on the market.
L-Theanine works in the brain to fight
stress by increasing alpha wave activity. There are all kinds of
different waves in the brain.
Beta waves are the stress-producing waves, delta waves cause you
to be sleepy, and alpha waves are the most powerful, responsible
for your levels of alertness, concentration and relaxation. Stress
literally attacks your ability to remain alert, feel at ease, and
tackle difficulties. (Creative people are actually proven to have
more alpha waves than other folks.) Stress diminishes these alpha
waves, which is why when you’re stressed, you have a hard
time focusing. This is where L-Theanine comes in.
L-Theanine increases alpha waves, helping
your brain handle stress. But that’s not all. L-Theanine
has been proven, in over a dozen studies, to promote more refreshing
sleep, to help support
normal blood pressure ranges, and to increase concentration and
focus. L-Theanine has also been shown to help support immune
function.
No side effects have ever
been documented. A daily dose of 100-200 mg is usually
what’s recommended. Proloftin contains 100
mg per two-capsule dose (and 200 mg if you double the daily dosage)
Click Here to see our sources and read what a scientific
abstract has to say about L-Theanine.
Magnolia bark has been used
since the dawn of the first millennia in China to
help balance energy or “chi”.
Translated into Western scientific language, magnolia bark helps
to balance unusually high cortisol levels, as occur when we are
under stress.
Magnolia bark not only soothes our frazzled nerves and eases nervous
energy, it comforts digestive troubles and aids stomach processes.
Magnolia bark has two compounds, called biphenols. One calms
and the other stops excess cortisol production.
Magnolia bark has always been used to relax and calm, but new studies
show that magnolia bark actually plays a role in helping to balance
cortisol levels. High cortisol levels have been linked to increased
risk for obesity, diabetes, heart disease, and low immunity.
Cortisol is the physical connection between mental or emotional
stress and their impact on physical health. Several studies have
also shown that magnolia bark may help reduce harmful neurotransmitters
in the brain, helping to alleviate stress and anxiety. And a
Japanese study shows that magnolia bark is up to a thousand times
more potent than vitamin E as an antioxidant.
At high dosages, magnolia bark can act as a mild depressant, causing
slight drowsiness. However, one would have to consume significant
quantities far beyond any recommended or commonly found dosage.
At normal dosages, magnolia bark is similar to L-Theanine, having
no depressant effect whatsoever, and is far safer than many sedative
drugs or depressants. 200-500 mg is the recommended range for
daily intake. Proloftin contains 100 mg per two capsules (200
mg if you double the dosage under high stress).
Click Here to see our sources and read what a scientific
abstract has to say about magnolia bark.
Beta-sitosterol is a (good) cholesterol-like compound
found in many foods, such as nuts, fruits, vegetables
and seeds. It’s
best absorbed in consistent, supplementary form, such as with a
pill or vitamin. There are hundreds of “sterols” in
the food supply, but beta-sitosterol has specific properties that
fight the affects of stress.
Beta-sitosterol has long
been known for its properties that help support healthy
cholesterol levels and a healthy immune system,
but beta-sitosterol also is excellent for helping muscles to
recover from stress, such as after a competition or an injury.
It’s best when taken after physical exertion or injury,
or during times of stress.
Doctors commonly recommend echinacea for its immune-boosting properties,
but studies show beta-sitosterol is actually more effective at
supporting immunity when the patient is suffering from stress.
Studies also point to significant benefits of beta sitosterol
as an essential nutrient for those suffering from stress as it
affects the muscles and immunity.
Beta-sitosterol isn’t dangerous, but to get enough in your
diet can be a rather high-caloric undertaking (several handfuls
of nuts or nut butters, or constant servings of vegetables throughout
the day). It’s one of the best immune-supporting nutrients
you can take when your body is undergoing stress – whether
physical, mental or emotional.
Click Here to see our sources and read what a scientific
abstract has to say about beta-sitosterol.
Also known as the “golden root,” the “arctic
root,” and “Crenulin.” Rhodiola is a plant that
grows in Siberia. It’s been used for thousands of years for
a variety of immune and stress purposes. It is known as an “adaptogen” because
it helps the body better adapt to stress – in other words,
to become more adept at handling future stressors. Rhodiola’s
main components are rosavin, rosarin, rosin and salidroside. These
ingredients help to move fatty acids, enabling greater metabolic
ability and can assist in weight loss while dieting. These active
ingredients also give the body a burst of energy in general, invigorating
the patient both at the cellular repair level and the mental mood
level.
Rhodiola not only fights
mental and emotional stress, but can help increase
athletic performance, support a healthy immune
system, improve concentration and alertness, promote
a sense of well-being, and even help with weight
loss while dieting or exercising.
Studies point to effective
weight loss when rhodiola is consumed, but studies
also prove significant benefits for mood, energy
levels, concentration, and athletic enhancement.
It is able to effectively help alleviate certain
states of non-clinical mental depression, and to
help the body to process oxygen more efficiently.
This manifests as increased energy, vitality, wellbeing,
and possible loss of body fat.
Rhodiola has no known side
effects. The recommended dose is 100-300 mg per
day. Proloftin’s formula includes 100 mg
per two-capsule daily dose (200 mg if you double
the normal dosage).
Click Here to see
our sources and read what a scientific abstract
has to say about rhodiola rosea.
(Abstract: PS is a phospholipid enriched in the brain, validated
through double-blind trials for improving memory, learning, concentration,
word recall, and mood
in middle- aged and elderly subjects with dementia or age-related cognitive
decline. PS has an excellent benefit- to-risk profile. ALC is an energizer
and metabolic cofactor which also benefits various cognitive functions
in the middle-aged and elderly, but with a slightly less favorable benefit-to-risk
profile.
Kidd P.M. (1999).
" A review of nutrients and botanicals in the integrative management of
cognitive dysfunction."
Altern Med Rev 4: 144-161.
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(Abstract: Since ancient times, it has been said that
drinking green tea brings relaxation. The substance that is responsible for
a sense of relaxation, is theanine.
Theanine is a unique amino acid found almost solely in tea plants and the
main component responsible for the exotic taste of ‘green’ tea.
It was found that L-Theanine administered intraperitoneally to rats reached
the brain within 30 min without any metabolic change. Theanine also acts
as a neurotransmitter in the brain and decreased blood pressure significantly
in hypertensive rats. In general, animals always generate very weak electric
pulses on the surface of the brain, called brain waves. Brain waves are classified
into four types, namely small alpha, Greek, small beta, Greek, small delta,
Greek and straight theta, small theta, Greek-waves, based on mental conditions.
Generation of small alpha, Greek-waves is considered to be an index of relaxation.
In human volunteers, small alpha, Greek-waves were generated on the occipital
and parietal regions of the brain surface within 40 min after the oral administration
of theanine (50–200 mg), signifying relaxation without causing drowsiness.
- “L-Theanine—a unique amino acid of green tea and its relaxation
effect in humans”
Lekh Raj Juneja
Nutritional Foods Division, Taiyo Kagaku Co., Ltd, 1-3 Takaramachi, Yokkaichi,
Mie 510-0844, Japan Laboratory of Nutritional Biochemistry, School of Food
and Nutritional Sciences, The University of Shizuoka, 52-1 Yada, Shizuoka 422-8526,
Japan
Available online 17 December 1999.
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EEG in the rat. Biosci Biotechnol Biochem. 2000 Feb;64(2):287-93.
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T., Takeuchi, N. "Reduction Effect of Theanine on Blood Pressure and Brain
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(Abstract:Use of the elevated plus-maze experiment and
activity and traction tests in mice have revealed that seven daily treatments
with 0.2 mg kg(-1) and higher doses of honokiol, a neolignane derivative
extracted from Magnolia bark, had an anxiolytic effect without change in
motor activity or muscle tone. Diazepam, 1 mg kg(-1), had the same anxiolytic
potential as 0.2 mg kg(-1) honokiol but induced muscle relaxation. The aim
of this study was to determine whether honokiol had diazepam-like side-effects.
Mice treated with 1-10 mg kg(-1) diazepam, but not those treated with 0.1-2
mg kg(-1) honokiol, for 12 days showed withdrawal symptoms characterized
by hyperactivity and running-fit when they were challenge-administered intraperitoneal
flumazenil (10 mg kg(-1)) 24 h after the last treatment with diazepam. Oral
diazepam (0.5-2 mg kg(-1), 10 min before) dose-dependently prolonged hexobarbital
(100 mg kg(-1), i.p.)-induced sleeping, disrupted learning and memory, and
inhibited (+)-bicuculline (40 mg kg(-1), i.p.)-induced death. Honokiol (0.2-20
mg kg(-1), p.o., 3 h before) had no such effects. The prolongation by diazepam
(1 mg kg(-1)) of hexobarbital-induced sleeping was not modified by honokiol
(0.2-20 mg kg(-1)). These results suggest that honokiol is less likely than
diazepam to induce physical dependence, central depression and amnesia at
doses eliciting the anxiolytic effect. It is also considered that honokiol
might have no therapeutic effect in the treatment of convulsion.
-J Pharm Pharmacol. 1999 Jan;51(1):97-103.
Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no
diazepam-like side-effects in mice.
Kuribara H, Stavinoha WB, Maruyama Y.
Department of Neuropsychopharmacology (Tsumura), Gunma University School of
Medicine, Maebashi, Japan.
1. Hou YC, Chao PD, Chen SY. Honokiol and magnolol
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of two oriental herbal drugs in Japan attributed to honokiol from magnolia
bark. J Pharm Pharmacol. 2000 Nov;52(11):1425-9.
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of honokiol, an anxiolytic agent present in extracts of Magnolia bark, evaluated
by an elevated plus-maze test in mice. J Pharm Pharmacol. 1998 Jul;50(7):819-26.
4. Kuribara H, Stavinoha WB, Maruyama Y. Honokiol, a putative anxiolytic agent
extracted from magnolia bark, has no diazepam-like side effects in mice. J
Pharm Pharmacol. 1999 Jan;51(1):97-103.
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(Abstract:Laboratory and human studies have shown us that
when sterols and sterolins are administered together, they enhance the immune
system.(1) Thus, sterols and sterolins may have some benefit in A**S and
H*V therapy. They do so by stimulating the activity of the immune system,
which helps control the multiplication of the virus.(2) Also, in a trial
with individuals running a marathon race, the blood work of those taking
the sterol/sterolin combination revealed significant increases in total white
blood cell count as well as in several lymphocyte counts and better ratios
of cortisol to DHEAs.(3) See below for (3):
(3): A pilot study was undertaken to investigate the effects
of the intake of capsules containing the plant sterols and sterolins (BSS:BSSG
mixture) on selected immune parameters of volunteers participating in an
ultra-marathon in Cape Town, South Africa. Those runners having received
active capsules (n=9) showed less neutrophilia, lymphopenia and leukocytosis
when compared to their counterparts having received placebo capsules (n=8):
the placebo treated individuals showed significant increases in their total
white blood cell numbers as well as in their neutrophils (p=0.03 and 0.03
respectively). Furthermore, statistically significant increases within lymphocyte
subsets were observed in the runners having received the active capsules:
CD3+ cells increased (p=0.02) as did CD4+ cells (p=0.03). In parallel, the
BSS:BSSG capsules decreased the plasma level of IL6 in the runners using
the active capsules (p=0.08) and significantly decreased the cortisol: DHEAs
ratio (p=0.03), suggesting that these volunteers had less of an inflammatory
response and were less immune suppressed during the post-marathon recovery
period. These findings justify further investigations into the use of the
phytosterols to prevent the subtle immunosuppression associated with excessive
physical stress.
-Bouic PJ, Clark and A, Lamprecht J
5/1999
Int J Sports Med
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(Abstract:Rhodiola rosea is a popular plant in traditional
medical systems in Eastern Europe and Asian with a reputation for stimulating
the nervous system, decreasing depression, enhancing work performance, eliminating
fatigue, and preventing high altitude sickness. Rhodiola rosea has been categorised
as an adaptogen by Russian researchers due to its observed ability to increase
resistance to a variety of chemical, biological, and physical stresses. Its
claimed benefits include antidepressant, antic****r, cardioprotective, and
central nervous system enhancement. Research also indicates great utility
in asthenia conditions (decline in work performance, sleep difficulties,
poor appetite, irritability, hypertension, headaches, and fatigue) developing
subsequent to intense physical or intellectual strain. The adaptogenic, cardiopulmonary
protective, and central nervous system activities of Rhodiola rosea have
been attributed primarily to its ability to influence levels and activity
of monoamines and opioid peptides such as beta-endorphins.
Altern Med Rev 2001; Jun, 6(3): 293-302.
" Rhodiola rosea: A possible plant adaptogen."
1. Linh PT, Kim YH, Hong SP, Jian JJ, Kang JS.
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in ischemic and reperfusion heart damage in vitro. Eksp Klin Farmakol 1997
May-Jun;60(3):34-6.
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placebo-controlled pilot study of the stimulating and adaptogenic effect of
Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during
an examination period with a repeated low-dose regimen. Phytomedicine 2000
Apr;7(2):85-9.
6. Wang S, Wang FP. Studies on the chemical components of Rhodiola crenulata.
Yao Hsueh Hsueh Pao. 1992;27(2):117-20.
7. Wang S, You XT, Wang FP. HPLC determination of salidroside in the roots
of Rhodiola genus plants. Yao Hsueh Hsueh Pao. 1992;27(11):849-52.
8. Xu J, Xie J, Feng P, Su Z. Oxygen transfer characteristics in the compact
callus aggregates of Rhodiola sachalinensis. Chin J Biotechnol 1998;14(2):99-107.
9. Yoshikawa M, Shimada H, Horikawa S, Murakami T, Shimoda H, Yamahara J, Matsuda
H. Bioactive constituents of Chinese natural medicines. IV. Rhodiolae radix.
Chem Pharm Bull (Tokyo) 1997 Sep;45(9):1498-503.
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